PMS/PMDD Treatment Trial

We are presently seeking women who are between the ages of 18 and 48 and suffer from a severe form of PMS called Premenstrual Dysphoric Disorder (PMDD) to participate in a clinical research trial (HIC 0609001839) funded by the National Institutes of Mental Health. The study is investigating “symptom-onset” dosing of Sertraline (Zoloft) as an effective treatment for PMDD.  With “symptom onset” dosing, you only take the study medication on those days when you experience your moderate to severe symptoms prior to getting your period. This means that women can appreciate the benefit of medication while not needing to take pills all month long.  Eligible women receive free care and study medication and can earn up to $325 for their participation. For more details, go to www.sospmdd.com or call Kari at (203) 764-5719 or  Email Kari for info. 

Basic Study Qualifications

• Female
• Ages 18-48
• Has regular menstrual periods
• Experiences PMS/PMDD symptoms every month
• Not currently depressed or taking prescription anti-depressant or anti-anxiety medication
• Not planning to become pregnant in the next 12 months
• Using a reliable form of birth control

Getting Started

• Please call us at (203) 764-5719 for a free, confidential evaluation of your premenstrual symptoms. 
• We will conduct a brief phone interview to determine preliminary eligibility, and then offer to schedule an office visit.
• At the office visit, we will take a more detailed medical history and ask you to begin participating by rating your symptoms.
• You will be required to rate your symptoms on a daily basis for at least two full menstrual cycles. This allows us to accurately diagnosis PMS or PMDD.
• If diagnosed as having PMDD, you will be randomly selected to either receive the study medication (Zoloft) or placebo (sugar pill).

Contact Us

• New Haven 203-764-5719
• Toll Free: 1-866-600-MOOD

 HIC#0609001839